2025-10-24
This dataset include 463 confirmed cases admitted from 2018-08-05 to 2019-07-15.
56% women and 2% children ≤5 years .
150 confirmed deaths reported for an average CFR of 32%.
These complications are inferred from laboratory results :
| Time from Onset to Admission by Outcome | ||||
|---|---|---|---|---|
| Outcome | N | Mean (days) | Median (days) | IQR (days) |
| Deceased | 147 | 6.1 | 5.0 | 4.5 |
| Recovered | 253 | 4.2 | 3.0 | 4.0 |
| Characteristic | N | n_obs | Event N | OR | 95% CI | p-value | Significance1 | Direction |
|---|---|---|---|---|---|---|---|---|
| CT at admission | 354 | 354 | 134 | 0.69 | 0.63, 0.76 | <0.001 | *** | ⬇ |
| Delay from admission | 354 | 354 | 134 | 1.13 | 1.03, 1.24 | 0.009 | ** | ⬆ |
| Remdesivir (GS-5734) | 112 | 5.13 | 1.40, 18.7 | 0.013 | * | ⬆ | ||
| Zmapp | 22 | 13.1 | 2.10, 81.8 | 0.006 | ** | ⬆ | ||
| Difficulty breathing anytime | 43 | 5.00 | 1.66, 15.1 | 0.004 | ** | ⬆ | ||
| Fatigue/weakness anytime | 302 | 3.65 | 1.02, 13.0 | 0.046 | * | ⬆ | ||
| Signs of dehydration anytime | 40 | 0.29 | 0.09, 0.92 | 0.036 | * | ⬇ | ||
| Abbreviations: CI = Confidence Interval, OR = Odds Ratio | ||||||||
| 1 Odds ratios (OR) obtained by exponentiating the logistic regression coefficients (β). OR > 1 indicates increased odds of the outcome; OR < 1 indicates decreased odds. | ||||||||
| Characteristic | N | n_obs | Event N | OR | 95% CI | p-value | Significance1 | Direction |
|---|---|---|---|---|---|---|---|---|
| Ebola treatment | 354 | 40 | ||||||
| None | 28 | — | — | |||||
| REGN3470-3471-3479 | 111 | 2.88 | 0.45, 58.7 | 0.35 | ⬆ | |||
| Remdesivir (GS-5734) | 112 | 1.07 | 0.14, 22.6 | 0.96 | ⬆ | |||
| Zmapp | 22 | 1.29 | 0.09, 35.8 | 0.86 | ⬆ | |||
| mAb114 | 79 | 0.77 | 0.09, 17.2 | 0.83 | ⬇ | |||
| REGN3470-3471-3479, Remdesivir (GS-5734) | 1 | 0.00 | >0.99 | ⬇ | ||||
| mAb114, Remdesivir (GS-5734) | 1 | 0.00 | >0.99 | ⬇ | ||||
| Total NaCl administered | 354 | 354 | 40 | 1.00 | 1.00, 1.00 | 0.067 | . | ⬆ |
| Experimental treatment | 354 | 40 | ||||||
| No | 209 | — | — | |||||
| Yes | 145 | 2.74 | 1.16, 6.73 | 0.024 | * | ⬆ | ||
| Hyperkaliemia | 354 | 40 | ||||||
| No | 347 | — | — | |||||
| Yes | 7 | 19.7 | 2.15, 219 | 0.009 | ** | ⬆ | ||
| hypokaliemia | 354 | 40 | ||||||
| No | 344 | — | — | |||||
| Yes | 10 | 12.5 | 2.46, 58.9 | 0.001 | ** | ⬆ | ||
| rhabdomyolysis | 354 | 40 | ||||||
| No | 335 | — | — | |||||
| Yes | 19 | 41.5 | 12.2, 166 | <0.001 | *** | ⬆ | ||
| Severe Hypoglycemia | 354 | 40 | ||||||
| No | 348 | — | — | |||||
| Yes | 6 | 20.1 | 1.70, 239 | 0.015 | * | ⬆ | ||
| Abbreviations: CI = Confidence Interval, OR = Odds Ratio | ||||||||
| 1 Odds ratios (OR) obtained by exponentiating the logistic regression coefficients (β). OR > 1 indicates increased odds of the outcome; OR < 1 indicates decreased odds. | ||||||||
EVD - North Kivu 2019